George Seabrook Bryan (May 22, 1809 – September 28, 1905) was a United States federal judge.
Born in Charleston, South Carolina, Bryan read law to enter the bar.
On February 9, 1866, Bryan was nominated by President Andrew Johnson to a seat on the United States District Court for the District of South Carolina vacated by Andrew Gordon Magrath. Bryan was confirmed by the United States Senate on March 12, 1866, and received his commission the same day. Bryan's service was terminated on September 1, 1886, due to retirement.
He died in Flat Rock, North Carolina.